Opportunity Information: Apply for 7200AA20RFA00007

USAID's STOP Spillover (Strategies To Prevent Spillover) is a discretionary health-focused funding opportunity intended to support a large, multi-partner effort to prevent emerging zoonotic viruses from jumping from animals to humans and, when spillover does occur, to reduce the chances that infections will amplify and spread further. The program is designed to build on both existing evidence and new research to create practical, testable interventions at the points where people and animals interact most intensely and where transmission risks are highest. A second major emphasis is on limiting onward transmission in high-risk settings after spillover, with health care facilities specifically noted as key locations where amplification and spread can occur if infection prevention and control measures are insufficient.

The central goal of STOP Spillover is to improve understanding of how zoonotic viral spillover happens and to translate that understanding into measurable reductions in risk. In practice, this means the awardee would be expected to develop, deploy, and evaluate interventions across high-risk animal-human interfaces, particularly those involving wildlife, since the opportunity highlights wildlife-to-human spillover as the main strategic focus. The program also explicitly extends beyond the initial animal-to-human event by addressing what happens next in people, aiming to curb amplification and spread once a virus has entered human populations. Taken together, the effort is framed as a prevention and risk-reduction program that combines evidence generation with real-world implementation and evaluation, rather than research alone.

The opportunity is offered as a cooperative agreement, which typically indicates substantial involvement by USAID during implementation compared with a standard grant. The funding is authorized under the Foreign Assistance Act of 1961 (as amended) and would be administered under the federal assistance rules in 2 CFR 200 (Uniform Administrative Requirements, Cost Principles, and Audit Requirements for Federal Awards) along with USAID's additional requirements in 2 CFR 700 and any other terms specified in the award's Section F. These references signal the compliance environment recipients must be prepared to meet, including financial management, reporting, allowable cost principles, and audit readiness consistent with federal award standards.

Eligibility is unrestricted, meaning USAID is open to applications from any qualified entity type, subject to any clarifications in the full notice. The opportunity number is 7200AA20RFA00007, and it is associated with CFDA 98.001. USAID anticipated making one award, with an award ceiling of up to $100,000,000, indicating the intent to fund a single, large prime implementer that can coordinate complex technical work across multiple geographies and disciplines. The notice was created on May 1, 2020, with an original closing date of June 1, 2020.

  • The Agency for International Development in the health sector is offering a public funding opportunity titled "STOP Spillover" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 98.001.
  • This funding opportunity was created on May 01, 2020.
  • Applicants must submit their applications by Jun 01, 2020. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $100,000,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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