Opportunity Information: Apply for RFA DK 26 309

This Notice of Funding Opportunity (NOFO) is a single-source renewal from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health (NIH), to continue operating the Scientific and Data Coordination Center (SDCC) for the Liver Cirrhosis Network. The goal is continuity: NIDDK is not opening a broad competition for multiple institutions, but instead is requesting a renewal application from the existing, designated organization to keep providing the network-wide scientific support and data coordination services needed to run and sustain the Liver Cirrhosis Network. The award mechanism is a cooperative agreement (U24), which typically means the project will be carried out with substantial NIH involvement and ongoing collaboration, rather than operating as a fully independent research grant.

Only one applicant is eligible to apply: Northwestern University. This is explicitly a single-source opportunity, so other U.S. institutions, organizations, or consortia cannot submit as the applicant organization under this NOFO. In addition, foreign participation is tightly restricted. Non-U.S. entities are not eligible to apply, non-U.S. components of U.S. organizations are not eligible, and foreign components (as defined by NIH policy) are not allowed. In practical terms, this keeps the SDCC work and formal project components within the United States and under the eligible domestic institution.

Even though the opportunity is single-source, it is not automatic funding. The renewal application will go through standard NIH peer review, and funding depends on the application being judged meritorious. The NOFO emphasizes that if the renewal application does not meet the expected scientific, technical, and operational standards, it will not be funded. This sets a clear expectation that the applicant must demonstrate strong performance, a credible plan for continued coordination center operations, and the ability to meet the network’s ongoing needs.

The funding listing identifies the opportunity as discretionary and in the health activity category, under CFDA (Assistance Listing) 93.847. The opportunity number is RFA-DK-26-309. NIDDK expects to make one award, consistent with the single-source structure, with an award ceiling of $1,850,000. The original closing date is January 27, 2027, and the NOFO creation date is January 9, 2026. The “clinical trial optional” designation means the SDCC may propose activities that include clinical trial-related components if appropriate, but a clinical trial is not required as a condition of applying under this announcement.

Overall, this NOFO is best understood as a continuation action to keep a central coordination hub in place for the Liver Cirrhosis Network, ensuring that the network’s studies and related activities have consistent scientific coordination, data management and harmonization, and the kind of centralized infrastructure that multi-site research programs typically need to function smoothly over time.

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Single Source Renewal for the Continuation of the Liver Cirrhosis Network: Scientific and Data Coordination Center (U24 Clinical Trial Optional)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847.
  • This funding opportunity was created on 2026-01-09.
  • Applicants must submit their applications by 2027-01-27.
  • Each selected applicant is eligible to receive up to $1,850,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others.
Apply for RFA DK 26 309

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