Opportunity Information: Apply for CDC RFA EH18 1804

The grant opportunity titled "Newborn Screening New Condition Implementation: Capacity Building and Quality Improvement through Data Harmonization" (Funding Opportunity Number: CDC RFA EH18 1804) is a discretionary federal funding program run by the U.S. Department of Health and Human Services through the Centers for Disease Control and Prevention (CDC), specifically within NCEH. It is offered as a cooperative agreement, which usually means the CDC expects to have an active partnership role during the project period rather than simply issuing funds with minimal involvement. The overall purpose of the opportunity is to increase the number of U.S. states and territories that have fully implemented newborn screening programs, with a particular emphasis on improving implementation through capacity building, quality improvement, and harmonizing data practices so programs can more consistently track, manage, and evaluate screening activities and outcomes.

In practical terms, the opportunity is aimed at strengthening how newborn screening programs adopt and operationalize screening for new conditions, and at making the underlying data systems and workflows more compatible and comparable across jurisdictions. "Capacity building" signals investments in the foundational capabilities a program needs to reliably deliver screening, follow-up, and reporting at scale. "Quality improvement" points to structured efforts to make programs more effective and consistent over time, often by measuring performance, identifying gaps, and implementing changes that improve timeliness, accuracy, and completeness. "Data harmonization" highlights a focus on aligning data elements, definitions, and processes so that information from different states and territories can be aggregated, compared, or shared more efficiently, which supports both day-to-day program management and broader evaluation of implementation progress.

Eligibility is listed as unrestricted, meaning the competition is open to any type of entity as long as it meets any additional eligibility conditions described in the full notice. The funding instrument is categorized under health (CFDA 93.065). The award ceiling is $300,000 per award, and CDC anticipated making about 10 awards under this announcement. The opportunity was created on April 25, 2018, with an original closing date of June 29, 2018, and applications were required to be submitted electronically by 5:00 p.m. Eastern Time on the due date.

Overall, this funding opportunity supports efforts that help jurisdictions move from partial or developing capacity to full implementation of newborn screening for newly added conditions, while also improving the quality and comparability of the data that newborn screening programs rely on. The intent is to speed and strengthen implementation across states and territories by pairing program improvement work with better-aligned data systems, which can make it easier to monitor progress, identify barriers, and demonstrate consistent program performance nationwide.

  • The Department of Health and Human Services, Centers for Disease Control - NCEH in the health sector is offering a public funding opportunity titled "Newborn Screening New Condition Implementation: Capacity Building and Quality Improvement through Data Harmonization" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.065.
  • This funding opportunity was created on Apr 25, 2018.
  • Applicants must submit their applications by Jun 29, 2018 Electronically submitted applications must be submitted no later than 500 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $300,000.00 in funding.
  • The number of recipients for this funding is limited to 10 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for CDC RFA EH18 1804

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Frequently Asked Questions (FAQs)

What is the title of this grant opportunity?

The opportunity is titled "Newborn Screening New Condition Implementation: Capacity Building and Quality Improvement through Data Harmonization".

What is the funding opportunity number?

The Funding Opportunity Number is CDC RFA EH18 1804.

Which federal agency is offering this funding?

This is a discretionary federal funding program offered by the U.S. Department of Health and Human Services (HHS) through the Centers for Disease Control and Prevention (CDC), specifically within NCEH.

What type of funding mechanism is this?

This opportunity is offered as a cooperative agreement, which generally means CDC expects to play an active partnership role during the project period rather than only providing funds with minimal involvement.

What is the overall purpose of the program?

The purpose is to increase the number of U.S. states and territories that have fully implemented newborn screening programs, with a particular emphasis on strengthening implementation for new conditions through capacity building, quality improvement, and data harmonization.

Who is this opportunity intended to help?

The opportunity is aimed at strengthening how newborn screening programs in U.S. states and territories adopt and operationalize screening for new conditions, and at improving how programs manage and compare data across jurisdictions.

What does "new condition implementation" mean in this context?

It refers to the work needed for newborn screening programs to adopt and fully operationalize screening for newly added conditions, moving from partial or developing capacity to consistent, full implementation.

What does "capacity building" mean for this opportunity?

"Capacity building" signals investments in the foundational capabilities a newborn screening program needs to reliably deliver screening, follow-up, and reporting at scale.

What does "quality improvement" mean for this opportunity?

"Quality improvement" points to structured efforts to improve program performance over time, typically by measuring performance, identifying gaps, and implementing changes that improve things like timeliness, accuracy, and completeness.

What does "data harmonization" mean for newborn screening programs?

"Data harmonization" highlights aligning data elements, definitions, and processes so information from different states and territories can be aggregated, compared, or shared more efficiently. This supports both day-to-day management and broader evaluation of implementation progress.

Why is data harmonization emphasized in this funding opportunity?

The intent is to make newborn screening data practices more compatible and comparable across jurisdictions, which can make it easier to track, manage, evaluate, and demonstrate implementation progress nationwide.

How does this opportunity aim to improve newborn screening nationwide?

By pairing program improvement work (capacity building and quality improvement) with better-aligned data systems (data harmonization), the program aims to speed and strengthen implementation across states and territories and support consistent monitoring of outcomes and barriers.

Is eligibility limited to specific entity types?

Eligibility is listed as unrestricted, meaning the competition is open to any type of entity, as long as it meets any additional eligibility conditions described in the full notice.

What is the CFDA or program area for this funding?

The funding instrument is categorized under health with CFDA 93.065.

What is the maximum award amount (award ceiling)?

The award ceiling is $300,000 per award.

How many awards did CDC anticipate making?

CDC anticipated making approximately 10 awards under this announcement.

When was the funding opportunity created?

The opportunity was created on April 25, 2018.

What was the original application closing date?

The original closing date was June 29, 2018.

How were applications required to be submitted?

Applications were required to be submitted electronically.

What was the application submission deadline time zone and time?

Applications were due by 5:00 p.m. Eastern Time on the due date.

What kinds of improvements are applicants expected to focus on?

Based on the description, the focus is on improving the ability to implement screening for new conditions through capacity building, quality improvement, and harmonized data practices that allow more consistent tracking, management, and evaluation of screening activities and outcomes.

What is CDC's expected role during the project period?

Because this is a cooperative agreement, CDC is expected to have an active partnership role during the project period, rather than acting only as a pass-through funder.

How does this opportunity relate to states and territories that are not yet fully implemented?

The opportunity supports efforts that help jurisdictions move from partial or developing capacity to full implementation of newborn screening for newly added conditions, while improving the quality and comparability of the data those programs rely on.

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