Opportunity Information: Apply for CDC RFA GH22 2222

The Centers for Disease Control and Prevention (CDC), under the U.S. Department of Health and Human Services, offered a PEPFAR-funded cooperative agreement opportunity titled "Comprehensive Community-based Programming to Maintain HIV Epidemic Control in Eswatini." The grant was published under Funding Opportunity Number CDC RFA GH22 2222 (CFDA 93.067) and was open to essentially any type of applicant (unrestricted eligibility, with any limits only if specified elsewhere in the notice). Applications were due February 28, 2022, by 11:59 pm ET, and CDC anticipated making two awards.

The purpose of the opportunity was to support community-based, comprehensive, evidence-based programming designed to help Eswatini sustain HIV epidemic control, specifically concentrating on the Manzini and Lubombo regions. The program emphasis reflects PEPFAR and broader global HIV control strategies: services should be client-centered, coordinated across sectors, and designed so that local systems can increasingly sustain and manage the work over time. A major expectation is strong collaboration with health services and also with social welfare systems, faith-based organizations, civil society, and other community structures, so that prevention, testing, treatment support, and protection services function as an integrated community response rather than as isolated projects.

Although the notice lists an "Award Ceiling for Year 1" as 0 (meaning no fixed per-award cap was stated for the first year), CDC projected an approximate total of $4,500,000 in funding for Year 1 across the program, contingent on funds being available. Because the instrument is a cooperative agreement, CDC would typically expect to have substantial involvement in implementation through ongoing technical direction, coordination expectations, and performance monitoring, rather than operating as a purely hands-off funder.

Programmatically, the NOFO prioritizes several interconnected areas. First is community-based HIV and gender-based violence (GBV) prevention, with a strong focus on reducing HIV acquisition risk among adolescent girls and young women (AGYW). Alongside that, the opportunity highlights expanding voluntary medical male circumcision (VMMC) coverage among adolescent boys and young men (ABYM), reflecting VMMC's role as a proven HIV prevention intervention in high-burden settings. Another priority is improving community case identification and linkage approaches for HIV and tuberculosis (TB), aiming to find people who are not yet diagnosed or not yet in care and connect them efficiently to appropriate services. The NOFO also calls for expanded community-based differentiated service delivery models, which generally means adapting service frequency, location, and delivery methods to meet clients' needs (for example, community ART refills, client-tailored follow-up, or streamlined models that reduce unnecessary clinic visits while maintaining quality of care). Finally, it places emphasis on strengthening the capacity of people living with HIV (PLHIV) networks, civil society organizations (CSOs), faith communities, and other local structures so they can deliver or support HIV, TB, and GBV services in a sustainable way.

A recurring theme throughout the opportunity is resilience and flexibility. CDC signals that the community systems and programming supported by this award should be able to keep functioning and adapt during health emergencies, environmental disruptions, or political instability, and should be structured so they can also be leveraged to respond to emerging public health needs beyond HIV when required. In practical terms, the NOFO is aiming to fund not only service delivery and prevention activities, but also durable community infrastructure, coordination mechanisms, and local capacity that help Eswatini maintain epidemic control over the long term.

  • The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Comprehensive Community-based Programming to Maintain HIV Epidemic Control in Eswatini under the President's Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
  • This funding opportunity was created on Dec 30, 2021.
  • Applicants must submit their applications by Feb 28, 2022 Electronically submitted applications must be submitted no later than 1159 pm ET on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 2 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for CDC RFA GH22 2222

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Frequently Asked Questions (FAQs)

1) What is the title of this CDC funding opportunity?

The opportunity is titled "Comprehensive Community-based Programming to Maintain HIV Epidemic Control in Eswatini."

2) Which agency is offering this grant?

The opportunity was offered by the Centers for Disease Control and Prevention (CDC) under the U.S. Department of Health and Human Services (HHS).

3) Is this opportunity funded through PEPFAR?

Yes. The notice describes it as a PEPFAR-funded cooperative agreement.

4) What is the Funding Opportunity Number (NOFO number)?

The Funding Opportunity Number is CDC RFA GH22 2222.

5) What is the CFDA number listed for this opportunity?

The CFDA number listed is 93.067.

6) What type of funding instrument is this?

This is a cooperative agreement. That typically means CDC expects substantial involvement during implementation, including technical direction, coordination expectations, and performance monitoring.

7) Who was eligible to apply?

Eligibility was described as essentially unrestricted (open to any type of applicant), with any limitations only if specified elsewhere in the notice.

8) What was the application deadline?

Applications were due February 28, 2022, by 11:59 pm Eastern Time (ET).

9) How many awards did CDC anticipate making?

CDC anticipated making two awards.

10) What was the projected funding amount for Year 1?

CDC projected approximately $4,500,000 in total funding for Year 1 across the program, contingent on the availability of funds.

11) Was there a stated per-award maximum (ceiling) for Year 1?

The notice lists an "Award Ceiling for Year 1" as 0, which indicates no fixed per-award cap was stated for the first year.

12) What is the overall purpose of the program?

The purpose is to support community-based, comprehensive, evidence-based programming designed to help Eswatini sustain HIV epidemic control.

13) Which geographic areas in Eswatini were specifically emphasized?

The opportunity specifically concentrates on the Manzini and Lubombo regions.

14) What approach does the NOFO emphasize for service delivery?

The NOFO emphasizes client-centered services that are coordinated across sectors and designed so local systems can increasingly sustain and manage the work over time.

15) What kinds of partnerships or collaboration are expected?

Strong collaboration is expected with health services and also with social welfare systems, faith-based organizations, civil society, and other community structures so services function as an integrated community response rather than isolated projects.

16) What are the main program priority areas described in the NOFO?

The NOFO prioritizes: (1) community-based HIV and gender-based violence (GBV) prevention (with a strong focus on adolescent girls and young women), (2) expanding voluntary medical male circumcision (VMMC) among adolescent boys and young men, (3) improving community case identification and linkage for HIV and tuberculosis (TB), (4) expanding community-based differentiated service delivery models, and (5) strengthening capacity of PLHIV networks, civil society organizations, faith communities, and other local structures.

17) How does the opportunity address HIV and GBV prevention for adolescent girls and young women (AGYW)?

A key priority is community-based HIV and GBV prevention with a strong focus on reducing HIV acquisition risk among adolescent girls and young women (AGYW).

18) What is the role of VMMC in this program?

The NOFO highlights expanding voluntary medical male circumcision (VMMC) coverage among adolescent boys and young men (ABYM), describing it as a proven HIV prevention intervention in high-burden settings.

19) What does the NOFO mean by improving community case identification and linkage for HIV and TB?

It focuses on finding people who are not yet diagnosed or not yet in care and connecting them efficiently to appropriate HIV and TB services.

20) What are "community-based differentiated service delivery" models in the context of this NOFO?

Differentiated service delivery generally means adapting service frequency, location, and delivery methods to meet clients' needs. Examples mentioned include community ART refills, client-tailored follow-up, or streamlined models that reduce unnecessary clinic visits while maintaining quality of care.

21) What kinds of community capacity strengthening does the NOFO prioritize?

The NOFO emphasizes strengthening the capacity of people living with HIV (PLHIV) networks, civil society organizations (CSOs), faith communities, and other local structures so they can deliver or support HIV, TB, and GBV services in a sustainable way.

22) Does the opportunity focus only on direct service delivery?

No. The NOFO aims to fund service delivery and prevention activities as well as durable community infrastructure, coordination mechanisms, and local capacity to support long-term epidemic control.

23) What does the NOFO say about sustainability and local ownership?

It emphasizes designing programming so that local systems can increasingly sustain and manage the work over time, supported by strengthened community structures and coordination.

24) What does the NOFO mean by an "integrated community response"?

It means prevention, testing, treatment support, and protection services should work together through coordinated community and sector partnerships, rather than operating as separate, disconnected projects.

25) How does the NOFO address resilience and continuity during disruptions?

A recurring theme is that community systems and programming should be resilient and flexible, able to keep functioning and adapt during health emergencies, environmental disruptions, or political instability.

26) Can the community systems supported by this award be used for needs beyond HIV?

Yes. The NOFO notes that the structures supported should be able to be leveraged to respond to emerging public health needs beyond HIV when required.

27) What level of involvement should applicants expect from CDC under a cooperative agreement?

Because it is a cooperative agreement, CDC would typically expect substantial involvement through ongoing technical direction, coordination expectations, and performance monitoring, rather than acting as a purely hands-off funder.

28) Is the Year 1 funding amount guaranteed?

No. The approximately $4,500,000 projection for Year 1 is contingent on funds being available.

29) What is the long-term goal this opportunity is trying to support in Eswatini?

The NOFO is structured to help Eswatini maintain HIV epidemic control over the long term through comprehensive community programming, integrated coordination, and strengthened local capacity.

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